If you’re looking for the latest insight and fantasy baseball DFS advice ahead of Opening Day on Thursday, we have you covered. Whether you’re looking for a lineup to stack, a specific hitter to approach, or maybe one or two pitchers to boost your rotation, we’ve got you.
Why You Should Stack the Dodgers Against the Diamondbacks
Every time you have a lineup as talented as the Dodgers’, they should be considered a worthy option to stack. The Dodgers will have Shohei Ohtani, Freddie Freeman, Mookie Betts, and Kyle Tucker (just to name a few) together in the same lineup, so this is a group that should command heavy attention in fantasy, especially since they’ll be playing at home.
The pitching matchup is also favorable since they’ll be facing Zac Gallen, who posted a career-worst 4.83 ERA and a 1.26 WHIP, his worst mark since 2021, in 33 starts last season. Playing at home in a star-studded lineup and against a struggling pitcher? The Dodgers are your best option if you’re planning to stack a lineup on Opening Day.
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Why the Houston Astros Are a Strong Stack Against Jose Soriano
The Astros have a strong lineup core, headlined by Yordan Alvarez but also featuring Jose Altuve, Isaac Paredes, Carlos Correa, and Christian Walker, just to mention a few. Alvarez will be hitting second, and the matchup against righty Jose Soriano looks promising on paper.
Soriano had a 4.26 ERA and a 1.40 WHIP across 31 starts in the 2025 regular season and owns a career 3.89 ERA across 51 starts and 91 appearances at the MLB level. It’s worth noting that Correa, Walker, Alvarez, and Jake Meyers have all found success against Soriano, making this lineup a decent option to stack in most formats.
Why Cubs Hitter Pete Crow-Armstrong Is a Top Opening Day Sleeper
The wind will be blowing in at over 20 mph in Wrigley Field for Thursday’s game, meaning not too many balls will be leaving the yard. However, that’s a scenario in which the speed on the basepaths could be an absolute game-changer.
No one on the Cubs roster emphasizes the blend of hitting ability and electrifying speed more than Crow-Armstrong, who recently signed a six-year contract extension with the Cubs worth $115 million. He should be extra motivated to carry the Cubs to victory on Opening Day as the new face of the franchise.
Two Starting Pitchers to Watch on Opening Day
Why Brewers Starter Jacob Misiorowski Is a Strong Play
Misiorowski couldn’t have asked for a better opponent to open the 2026 season, as he’ll be pitching at home against the Chicago White Sox, who have been one of the worst offenses in baseball in each of the last two seasons.
Misiorowski is starting on Opening Day solely because of the absences of Brandon Woodruff (lat) and Quinn Priester (wrist), but he should take full advantage of the opportunity against a White Sox offense that ranked 29th in baseball in total runs scored in 2025 with 647 (3.99 per game).
Why Rays Starter Drew Rasmussen Is a Safe Bet Against the Cardinals
Rasmussen was excellent in the 2025 season, which was also his first full season back from elbow surgery. He posted a 2.76 ERA and 127:37 K:BB over 150 innings and 31 starts, and he was named the Rays’ Opening Day starter back in mid-February. The pitching matchup is favorable, as the Cardinals are in full-rebuild mode and project to be one of the worst offenses in the National League in the 2026 fantasy baseball season.
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