If you still need some advice for your fantasy baseball lineup ahead of Saturday’s slate, we have recommendations for you. From potential lineups to stack to pitchers and hitters to keep a close eye on, here are four fantasy baseball targets you should consider for your DFS slate on March 28.
Why the Baltimore Orioles Are a Top DFS Lineup Stack for Saturday
The Orioles are one of the biggest bounce-back candidates ahead of the 2026 season, and a major reason is their offensive potential, with names like Gunnar Henderson and Pete Alonso carrying the load.
Still, the Orioles also have plenty of valuable hitters in their lineup, and the pitching matchup is favorable since Taj Bradley tends to struggle with command and control, an issue that’s particularly noticeable against left-handed hitters.
Aside from Alonso and Henderson, who are proven producers against any pitcher, the Orioles also have left-handed hitters such as Samuel Basallo, Colton Cowser, and Dylan Beavers in the lineup. This could be a favorable matchup for the Orioles’ lineup, especially since Camden Yards is now a more hitter-friendly environment following its recent modifications.
Why the Chicago Cubs Are a Strong Secondary DFS Stack
The Cubs have the potential to be one of the best offenses in the National League in 2026, but they didn’t show that on Opening Day in a 10-4 loss to the Nationals.
Still, this is a lineup that features Michael Busch, Pete Crow-Armstrong, Alex Bregman, and Dansby Swanson, even if Seiya Suzuki is out with a knee injury.
The Cubs will have the advantage of playing at home, and even though windy conditions are expected to affect Wrigley Field, they will be there for both teams. The Nationals will have Miles Mikolas on the mound, who has struggled mightily in his recent starts against the Cubs. Mikolas also allowed 9 homers at Wrigley Field in 2025.
Why Michael Busch Is a Top DFS Hitter for Saturday
The Cubs dropped their season opener against the Nationals after Washington scored 6 runs in the fourth inning. However, if there was one silver lining for Chicago, it was Busch’s performance.
The first baseman went 3-for-4 with a walk, 2 doubles, an RBI, and 2 runs scored in Thursday’s 10-4 loss, and with the Cubs in dire need of a win Saturday, they might rely on Busch to carry the offense once again as their leadoff hitter.
Busch is coming off a 2025 season in which he hit .261 with an .866 OPS, 34 homers, and 90 RBI across 155 games and 592 plate appearances.
Why You Should Target David Peterson as a Streaming Pitcher Option
David Peterson is one of the pitchers to watch when it comes to potential streaming alternatives. Citi Field is considered a pitcher-friendly environment, and he’ll be taking on a Pirates lineup that didn’t look very good on Opening Day on Thursday.
Peterson is a southpaw, meaning his presence in the lineup will limit the impact of Pittsburgh’s two biggest offseason additions on offense in Brandon Lowe and Ryan O’Hearn.
O’Hearn hit .278 vs. southpaws in 2025 across 109 plate appearances, whereas Lowe was even worse and hit .194 with 5 home runs and 9 RBI in 147 plate appearances against lefties last season.
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